PeDRA

Pediatric Dermatology Research Alliance

AD&PsO Ongoing

T regulatory cell dysfunction and Staphylococcus aureus infection enable atopic dermatitis onset and progression

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Principal Investigator: Hazel Wilkie, PhD Boston Children's Hospital Overview: Atopic dermatitis (AD, also called allergic eczema) affects 20% of children and 10% of adults. The dry, red, itchy skin lesions are often infected with bacteria. Intriguingly, skin bacterial burden increases prior … [Read more...] about T regulatory cell dysfunction and Staphylococcus aureus infection enable atopic dermatitis onset and progression

Evaluation of the Efficacy of Popular Over the Counter Ointments in Atopic Dermatitis: A Double Blinded Randomized Controlled Trial

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Principal Investigator: JiaDe Yu, MDMassachusetts General Hospital Overview: Atopic dermatitis (AD) or eczema is a common skin disease seen in 20% or more of children in the United States. There are many potential causes of AD but disorders in the skin barrier leads to increased water loss … [Read more...] about Evaluation of the Efficacy of Popular Over the Counter Ointments in Atopic Dermatitis: A Double Blinded Randomized Controlled Trial

Investigating the Role of Age, Race and Ethnicity in Response to Immunomodulating Agents in Children with Moderate to Severe Atopic Dermatitis

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Fellow Angel PaganPonce Health Sciences University Mentor Emma Guttman-Yassky, MD, PhDIchan School of Medicine at Mount Sinai Overview Up to 11% of United States children are affected by atopic dermatitis (AD) and one-third of these suffer from moderate-to-severe disease. The negative … [Read more...] about Investigating the Role of Age, Race and Ethnicity in Response to Immunomodulating Agents in Children with Moderate to Severe Atopic Dermatitis

The Impact of Topical Prescription Drug Delivery Devices in the Adherence and Ease of Use of Corticosteroids in Pediatric Patients with Atopic Dermatitis

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Fellow Wenelia BaghoomianOregon Health & Science University Mentor Eric Simpson, MDOregon Health & Science University Overview Atopic dermatitis (AD) is the most common pediatric inflammatory skin disease affecting 15-30% of children worldwide. Topical corticosteroids remain the … [Read more...] about The Impact of Topical Prescription Drug Delivery Devices in the Adherence and Ease of Use of Corticosteroids in Pediatric Patients with Atopic Dermatitis

Characterization of Non-Alcoholic Fatty Liver in Pediatric Psoriasis

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Fellow Jennifer Gionah LaboradaUniversity of California Riverside School of Medicine Mentor Wynnis Tom, MDUniversity of California San Diego Overview Psoriasis is a chronic inflammatory skin disease associated with overweight/obesity and increased cardiometabolic risk. One particularly … [Read more...] about Characterization of Non-Alcoholic Fatty Liver in Pediatric Psoriasis

Effects of poverty and environmental exposures across race and ethnicity in children with atopic dermatitis

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Fellow Emily Croce, MSN, APRN, CPNP-PCThe University of Texas at Austin School of Nursing Mentor Moise Levy, MDDell Medical School at The University of Texas at Austin Overview The purpose of this study is to understand the effects of living in a poor neighborhood on AD prevalence and … [Read more...] about Effects of poverty and environmental exposures across race and ethnicity in children with atopic dermatitis

TNF inhibitor-induced psoriasiform dermatitis in children: Clinical and mechanistic analyses

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Principal Investigators: Amy Paller, MDNorthwestern UniversityJennifer Boles-Scott, MDNorthwestern University Overview: Injectable medications that inhibit tumor necrosis factor (TNF) block inflammation in arthritis, inflammatory bowel disease, and psoriasis. However, there are reports of … [Read more...] about TNF inhibitor-induced psoriasiform dermatitis in children: Clinical and mechanistic analyses