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Evaluation of the Efficacy of Popular Over the Counter Ointments in Atopic Dermatitis: A Double Blinded Randomized Controlled Trial

April 6, 2022 By Katherine Devenport


Principal Investigator:

JiaDe Yu, MD
Massachusetts General Hospital

Overview:

Atopic dermatitis (AD) or eczema is a common skin disease seen in 20% or more of children in the United States. There are many potential causes of AD but disorders in the skin barrier leads to increased water loss from the skin thereby drying out the skin making it more prone to AD. Over the counter moisturizers such as Aquaphor, Cerave Ointment, Vaseline Ointment, and Vanicream Ointment are frequently recommended by dermatologists for the treatment and prevention of AD. While these products differ in their ingredients, there is currently no published evidence that one is superior to the other. The goal of this study is to evaluate the four moisturizing ointments in children with AD to see if we can determine which ointment is more efficacious in prevent dry skin and water loss.

Status:

This project was funded by a 2021 PeDRA Research Grant.

Filed Under: AD&PsO Ongoing, Atopic Derm & Psoriasis

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