Principal Investigator: Christina Boull, MD University of Minnesota Overview: This is a multi-center retrospective chart review of pediatric patients who have received MEK inhibitors and/or BRAF inhibitors to better document and describe the associated cutaneous changes. The use of targeted … [Read more...] about Cutaneous Findings in Children Receiving MEK and BRAF Inhibitors
Active Studies
Chronic Graft versus Host Disease
Principal Investigator: Dominique Pichard, MD National Institute of Arthritis and Musculoskeletal and Skin Diseases Overview: Chronic GVHD is a rare, but often debilitating, condition that occurs after stem cell transplant. The current diagnostic and management guidelines for cGVHD are based … [Read more...] about Chronic Graft versus Host Disease
Management of afebrile neonates with pustules
Principal Investigator: Christine Lauren, MD Columbia University Overview: The aim of this retrospective, multi-center study is to document the current practices of pediatric dermatologists across North America and establish recommendations for the evaluation and management of afebrile … [Read more...] about Management of afebrile neonates with pustules
Evaluation of skin care practices in the neonatal ICU setting
Principal Investigator: Christine Lauren, MD Columbia University Overview: The Survey of Skincare in Neonates to Update Guidelines (SoSNUG) project proposes to assess the practices and protocols regarding neonatal skin care that are currently utilized in newborn nurseries and NICUs across the … [Read more...] about Evaluation of skin care practices in the neonatal ICU setting
Topical Sirolimus for the Treatment of Vascular Anomalies
Principal Investigator Sheilagh Maguiness, MD University of Minnesota Overview: There are growing reports regarding the efficacy of oral M-TOR inhibitors such as sirolimus in the treatment of complex combined vascular malformations. There is strong rationale for the use of sirolimus/M-TOR … [Read more...] about Topical Sirolimus for the Treatment of Vascular Anomalies
PHACE Risk Based on Clinical Characteristics of Large Facial Hemangiomas: A Retrospective Cohort Study
Principal Investigators: Victoria Barrio, MD Rady Children's Hospital Colleen Cotton, MD Medical University of South Carolina Overview: This is a retrospective, multicenter study across fifteen sites in the US and Canada examining all children who were evaluated for PHACE syndrome (whether … [Read more...] about PHACE Risk Based on Clinical Characteristics of Large Facial Hemangiomas: A Retrospective Cohort Study
Retrospective Cohort Study of Ulcerated Hemangiomas
Principal Investigator: Esteban Fernandez Faith, MD Nationwide Children's Hospital Overview: The goal of the study is to assemble a large cohort of patients with ulcerated infantile hemangiomas to better characterize this complication in the era of beta-blockers. The study aims to determine … [Read more...] about Retrospective Cohort Study of Ulcerated Hemangiomas
Investigation of Somatic Mosaicism in PHACE Using Next-Generation Sequencing
Principal Investigator: Dawn Siegel, MD Medical College of Wisconsin Overview: This is a registry study, using next generation sequencing to better understand somatic mosaicism in PHACE Syndrome. Status: Enrollment ongoing. Participating Sites: … [Read more...] about Investigation of Somatic Mosaicism in PHACE Using Next-Generation Sequencing
