Principal Investigators:
Victoria Barrio, MD – Rady Children’s Hospital
Colleen Cotton, MD – Medical University of South Carolina
Overview:
This is a retrospective, multicenter study across fifteen sites in the US and Canada examining all children who were evaluated for PHACE syndrome (whether or not they ultimately received the diagnosis) over a five year period. Objectives of the study are to assemble a multicenter retrospective cohort of patients with large facial hemangiomas evaluated for PHACE syndrome with data regarding epidemiology, hemangioma characteristics, and comorbid anomalies; to perform sub-group analyses of the categories outlined above by hemangioma depth and location, including parotid hemangiomas; and to determine the positive predictive value of clinical features that will provide more data-driven and cost-effective screening of children with large facial hemangiomas.
Status:
Data collection is complete and two manuscripts are in preparation.