PeDRA

Pediatric Dermatology Research Alliance

Active Studies

Development of a Pediatric Lichen Sclerosus Grading Scale

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Principal Investigator: Kalyani Marathe, MD, MPHChildren's National Health System Overview: Lichen sclerosus (LS) is a chronic inflammatory disease that primarily affects the anogenital region. It usually presents with pruritus, pain, atrophy, sclerosis, depigmentation, hyperkeratosis, … [Read more...] about Development of a Pediatric Lichen Sclerosus Grading Scale

Developing an Outcome Measure for Morphea Disease Activity

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Co-Principal Investigators: Maria Teresa Garcia Romero, MD, MPHNational Institute of Pediatrics, Mexico City Yvonne Chiu, MD Medical College of Wisconsin Overview: Morphea is a complex condition that mainly affects children and lacks a good way to measure disease activity.  This … [Read more...] about Developing an Outcome Measure for Morphea Disease Activity

Atopic Dermatitis: An Assessment of Lesional Morphology by Race/Ethnicity

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Co-Principal Investigators: Minnelly Luu, MD University of Southern California Wynnis Tom, MD University of California, San Diego Overview: Although atopic dermatitis (AD) affects all races and skin types with shared features of relapses and pruritus, it is a heterogeneous disease … [Read more...] about Atopic Dermatitis: An Assessment of Lesional Morphology by Race/Ethnicity

Guidelines for Use of Methotrexate in Pediatric Inflammatory Skin Diseases

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Co-Principal Investigators: Elaine Siegfried, MD St. Louis University Heather Brandling-Bennett University of Washington Overview: Methotrexate is a time-honored drug, used for over 50 years for a wide variety of indications, across all routes of administration. Literature suggests there is … [Read more...] about Guidelines for Use of Methotrexate in Pediatric Inflammatory Skin Diseases

Patient education for children at risk for skin cancer

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Principal Investigator: Carrie Coughlin, MD Washington University School of Medicine Overview: Though children are at risk for skin cancer and cutaneous complications of immunosuppressive therapy, there is a paucity of pediatric-specific educational materials.  Moreover, there are no … [Read more...] about Patient education for children at risk for skin cancer

Melanoma and nonmelanoma skin cancer in children and young adults

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Co-Principal Investigators: Jen Huang, MD Harvard Medical School Larry Eichenfield, MD UCSD Overview: This study is a collaboration of 10 major hospitals across the country with the unified goal of improving our understanding of skin cancer in children.  It is a multi-center … [Read more...] about Melanoma and nonmelanoma skin cancer in children and young adults

Fatal Pediatric Melanoma Retrospective Study

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Principal Investigator: Elena Hawryluk, MD, PhD Massachusetts General Hospital Overview: Pediatric dermatologists have a strong interest in better understanding pediatric nevi and characterizing melanoma; the diagnostic challenge of pediatric melanomas can delay diagnosis, lead to deeper and … [Read more...] about Fatal Pediatric Melanoma Retrospective Study