Principal Investigator: Leslie Castelo-Soccio, MD, PhD Children's Hospital of Philadelphia Overview: Alopecia areata is an autoimmune disease that leads to hair loss. There is no approved therapy for this stigmatizing disease. Current off-label immune suppressive therapies can put children at … [Read more...] about Fecal Microbiome in Alopecia Areata
Inflammatory Skin Disease
Systemic Treatment of Atopic Dermatitis
Principal Investigator: Wynnis Tom, MD UCSD Overview: This is a prospective, observational study of traditional systemic agents for severe, refractory atopic dermatitis in children. We are comparing the efficacy and safety of oral cyclosporine, azathioprine, mycophenolate mofetil, and … [Read more...] about Systemic Treatment of Atopic Dermatitis
Retrospective Review of Topical Immunotherapy for Alopecia Areata
Principal Investigator: Nanette Silverberg, MD Mount Sinai Health System Overview: Alopecia areata (AA) is an autoimmune disease resulting in non-scarring hair loss of hair-bearing areas, most frequently the scalp with a lifetime incidence of 1-2%. This is a registry study intended to help … [Read more...] about Retrospective Review of Topical Immunotherapy for Alopecia Areata
Psoriasis and psoriasiform reactions in children receiving anti-TNF medications
Principal Investigators: Megha Tollefson, MD Mayo Clinic Amy Paller, MD Northwestern University Overview: Children on anti-TNF agents have been reported to develop psoriasis, but the majority of the literature is in the gastrointestinal (GI) literature and focuses on infliximab and … [Read more...] about Psoriasis and psoriasiform reactions in children receiving anti-TNF medications
Pediatric Psoriasis Comorbidity Screening Guidelines and Implementation and Education via an Electronic Platform
Principal Investigator: Wynnis Tom, MD UCSD Overview: Comorbidities are a significant burden for psoriasis patients, and this burden may be exacerbated in pediatric patients. PeDRA's Psoriasis Investigator Group (PsIG) members and other multidisciplinary experts worked to develop the first … [Read more...] about Pediatric Psoriasis Comorbidity Screening Guidelines and Implementation and Education via an Electronic Platform
Pediatric Contact Dermatitis Registry Using New Baseline Series for Children
Principal Investigator: Jeff Yu, MD Massachusetts General Hospital Overview: Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity reaction. Detection of through patch testing and avoidance of offending allergens are important for resolution of dermatitis. This condition has … [Read more...] about Pediatric Contact Dermatitis Registry Using New Baseline Series for Children
Hidradenitis Suppurativa in Pediatric Population
Principal Investigator: Irene Lara-Corrales, MD University of Toronto Overview: Epidemiologic data of hidradenitis suppurativa (HS) in children is lacking. By reviewing the clinical presentation and management of HS in children our goal is to better characterize this patient population and … [Read more...] about Hidradenitis Suppurativa in Pediatric Population
Development of a Pediatric Lichen Sclerosus Grading Scale
Principal Investigator: Kalyani Marathe, MD, MPHChildren's National Health System Overview: Lichen sclerosus (LS) is a chronic inflammatory disease that primarily affects the anogenital region. It usually presents with pruritus, pain, atrophy, sclerosis, depigmentation, hyperkeratosis, … [Read more...] about Development of a Pediatric Lichen Sclerosus Grading Scale