Principal Investigator: Amy Paller, MDNorthwestern University Overview: Psoriasis is a chronic inflammatory skin disease associated with early onset cardiovascular disease. Despite studies demonstrating high cholesterol, increased diabetes and higher rate of obesity in psoriasis, these … [Read more...] about Characterization of Lipoprotein Composition and Function in Pediatric Psoriasis Before and After Treatment
AD&PsO Ongoing
Understanding Racial/Ethnic Disparities in Health Care Utilization for Childhood Atopic Dermatitis
Principal Investigator: Junko Takeshita, MD, PhD, MSCEUniversity of Pennsylvania Overview: Atopic dermatitis (AD) is a common skin disease that disproportionately affects minority children and is associated with a large financial burden in the U.S. Racial/ethnic disparities in health care … [Read more...] about Understanding Racial/Ethnic Disparities in Health Care Utilization for Childhood Atopic Dermatitis
Discovering the Immune Phenotype of Morphologic Subsets of Atopic Dermatitis at the Single Cell Level
Fellow Carmel AghdasiUniversity of California, San Francisco Mentor Kelly Cordoro, MDUniversity of California, San Francisco Overview The purpose of this work is to characterize the immunologic signatures and clinical characteristics of a diverse population of pediatric patients with atopic … [Read more...] about Discovering the Immune Phenotype of Morphologic Subsets of Atopic Dermatitis at the Single Cell Level
Studying Topical Adherence in Atopic Dermatitis: What We Can Learn from Positive Outliers
Principal Investigator: Steven Feldman, MD, PhDWake Forest University Health Sciences Overview: Although topical medications are highly effective treatments for atopic dermatitis, poor treatment adherence can lead to poor treatment outcomes and unnecessary escalation of costly therapy. The … [Read more...] about Studying Topical Adherence in Atopic Dermatitis: What We Can Learn from Positive Outliers
The Relationship between the Cutaneous Microbiome and Skin Barrier in Infantile Atopic Dermatitis
Principal Investigator: Jennifer Schoch, MD University of Florida Co-Investigator: Reesa Monir, MD University of Florida Overview: Infantile atopic dermatitis (i.e. eczema) is a common pediatric skin condition leading to significant complications for patients and parents. Sleep … [Read more...] about The Relationship between the Cutaneous Microbiome and Skin Barrier in Infantile Atopic Dermatitis
Systemic Treatment of Atopic Dermatitis
Principal Investigator: Wynnis Tom, MD UCSD Overview: This is a prospective, observational study of traditional systemic agents for severe, refractory atopic dermatitis in children. We are comparing the efficacy and safety of oral cyclosporine, azathioprine, mycophenolate mofetil, and … [Read more...] about Systemic Treatment of Atopic Dermatitis
Psoriasis and psoriasiform reactions in children receiving anti-TNF medications
Principal Investigators: Megha Tollefson, MD Mayo Clinic Amy Paller, MD Northwestern University Overview: Children on anti-TNF agents have been reported to develop psoriasis, but the majority of the literature is in the gastrointestinal (GI) literature and focuses on infliximab and … [Read more...] about Psoriasis and psoriasiform reactions in children receiving anti-TNF medications
Pediatric Psoriasis Comorbidity Screening Guidelines and Implementation and Education via an Electronic Platform
Principal Investigator: Wynnis Tom, MD UCSD Overview: Comorbidities are a significant burden for psoriasis patients, and this burden may be exacerbated in pediatric patients. PeDRA's Psoriasis Investigator Group (PsIG) members and other multidisciplinary experts worked to develop the first … [Read more...] about Pediatric Psoriasis Comorbidity Screening Guidelines and Implementation and Education via an Electronic Platform
