Principal Investigator:
Elena Pope, MD, MSc
The Hospital for Sick Children
Overview:
Kaposiform hemangioendothelioma and tufted angioma are rare, benign but locally aggressive vascular tumors with potential for local complications (e.g. interfering with vital functions such as breathing, heart function, etc) and risk of bleeding due to trapping of the clothing factors within the tumor. Guidelines of care have been published in 2013. Since then, the medical treatment has changed and the first line medication in most instances is rapamycin. To date, practitioners still need answers to questions such as which type of tumors need to be treated, with what type of drugs and for how long treatment is needed. We propose to undertake a large multicenter study examining the clinical features, type of treatment and short- and long-term outcomes of patients with these rare entities. We believe that this study will add valuable information to the care of these patients and may serve the basis for updated care guidelines.
Status:
This project was funded by a 2023 PeDRA Research Grant.
