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Management of Reactive Infectious Mucocutaneous Eruption (RIME) in Children

February 27, 2023 By Katherine Devenport

Co-Principal Investigators:

Irene Lara-Corrales, MD, MSc
University of Toronto


Michele Ramien, MDCM, MSc
University of Calgary

Overview:

Reactive infectious mucocutaneous eruption (RIME) is a reaction of the skin and mucosa (moist linings of the body) to infections. The infections are usually in the body’s airways, and they trigger skin reactions that look like blisters or a burn.

RIME is a problem for kids because it happens more to kids than adults. We don’t know why it happens, or why some kids get RIME and others don’t. Most doctors don’t know what to do to help when a kid with RIME comes to their clinic or hospital. Right now, we don’t have instructions on RIME for doctors.

Our group of dermatologists (skin doctors) is interested in RIME. We want to make clear instructions for other doctors, so they know how to tell that a kid has RIME and how to make them better. To do this, we will review what is written about RIME in medical journals and books. Our group has experience looking after kids with RIME, so when there is not a clear answer from journals and books, we will use our experience to suggest what to do.

Status:

This was funded through a 2022 PeDRA Consensus Guidelines Grant.

Filed Under: Drugs and Bugs

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