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Characterizing the Cutaneous Late Effects in Pediatric Hematopoietic Stem Cell Transplantation Recipients

April 6, 2022 By Katherine Devenport


Principal Investigator:

Rebecca Levy, MD, FRCPC
Hospital for Sick Children, Toronto

Overview:

Hematopoietic stem cell transplantation (HSCT) is a procedure used to cure a variety of potentially fatal diseases, including cancers and genetic conditions. For HSCT survivors, we now understand there exist a variety of long-term complications that can impact different parts of the body, including the skin. The late skin complications of children who have undergone HSCT are poorly understood. This project aims to analyze data from linked provincial databases to define the risks and predictors of skin cancers in individuals who underwent HSCT at the Hospital for Sick Children. Furthermore, the project aims to enroll children from our specialized HSCT Late Effects clinic to better understand the spectrum of skin diseases, factors that might predict for these diseases, and determine impacts on overall quality of life. Ultimately, we hope that this study will improve the recognition and management of skin diseases in pediatric HSCT recipients to improve their overall care.

Status:

This project was funded by a 2021 Weston Career Development Award.

Filed Under: Skin Tumors and Reactions to Cancer Therapies

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