PeDRA

Pediatric Dermatology Research Alliance

Birthmark Studies

Multi Center Phenotype-Genotype Analysis of Vascular Overgrowth Syndromes

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Fellow Ashley NgMedical College of Wisconsin Mentor Beth Drolet, MDUniversity of Wisconsin - Madison Overview Vascular anomalies represent a diverse group of developmental disorders and affect patient-reported quality of life globally, but particularly mental health and emotional well-being … [Read more...] about Multi Center Phenotype-Genotype Analysis of Vascular Overgrowth Syndromes

Capillary Malformation-Arteriovenous Malformation Syndrome Guidelines

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Project Lead: Lara Wine Lee, MD, PhDMedical University of South Carolina Overview: Patients diagnosed with Capillary Malformation - Arteriovenous Malformation Syndrome present with multiple, small, flat areas of red color change in their skin, known as capillary malformations. Some patients … [Read more...] about Capillary Malformation-Arteriovenous Malformation Syndrome Guidelines

Examining How Virtual Reality Improves Children’s Coping During Dermatologic Procedures

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Principal Investigator: Annie Grossberg, MDJohns Hopkins Overview: Children who play virtual reality games have been found to experience less pain and anxiety during vaccination and venipuncture. The immersive experience of virtual reality provides distraction and promotes play during an … [Read more...] about Examining How Virtual Reality Improves Children’s Coping During Dermatologic Procedures

Towards a precision-based treatment for facial port wine birthmarks

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Principal Investigator: Lisa Arkin, MD University of Wisconsin, Madison Overview: Facial vascular stains affect 0.3-0.5% of newborns; they reduce quality of life due to soft tissue overgrowth, nodularity and life-altering, stigmatizing disfigurement. Laser treatment is the current standard of … [Read more...] about Towards a precision-based treatment for facial port wine birthmarks

Genomic and Non genomic Causes of Segmental Pigmentation Disorder

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Principal Investigator: Marcia Hogeling, MD University of California, Los Angeles Overview: Segmental Pigmentation Disorder (SegPD) is an uncommon skin condition affecting young children. Segmental Pigmentation Disorder consists of white and brown pigmented birthmarks that appear as large … [Read more...] about Genomic and Non genomic Causes of Segmental Pigmentation Disorder

Topical Sirolimus for the Treatment of Vascular Anomalies

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Principal Investigator Sheilagh Maguiness, MD University of Minnesota Overview: There are growing reports regarding the efficacy of oral M-TOR inhibitors such as sirolimus in the treatment of complex combined vascular malformations. There is strong rationale for the use of sirolimus/M-TOR … [Read more...] about Topical Sirolimus for the Treatment of Vascular Anomalies

PHACE Risk Based on Clinical Characteristics of Large Facial Hemangiomas: A Retrospective Cohort Study

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Principal Investigators: Victoria Barrio, MD Rady Children's Hospital Colleen Cotton, MD Medical University of South Carolina Overview: This is a retrospective, multicenter study across fifteen sites in the US and Canada examining all children who were evaluated for PHACE syndrome (whether … [Read more...] about PHACE Risk Based on Clinical Characteristics of Large Facial Hemangiomas: A Retrospective Cohort Study