Fellow Kennedy Gallagher, BAThomas Jefferson University Mentor Amy Paller, MDNorthwestern University Overview Atopic dermatitis (AD), also known as eczema, is the most common inflammatory skin disorder. Sleep disturbance occurs in most children affected by AD and has devastating … [Read more...] about Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children with Moderate/Severe Atopic Dermatitis
Atopic Derm & Psoriasis
Genetic Landscape of Pediatric Patients with Monogenic Susceptibilities to Atopic Dermatitis
Principal Investigator: Hassan Vahidnezhad, MSc, PhD Children's Hospital of Philadelphia Overview: Childhood eczema, also called atopic dermatitis (AD), is the most common skin disease in children, is characterized by inflammation and itching, and is often associated with a history of atopy … [Read more...] about Genetic Landscape of Pediatric Patients with Monogenic Susceptibilities to Atopic Dermatitis
The Influence of Childhood Experiences on Exacerbations of Atopic Dermatitis
Mentee Kennedy SparlingUniversity of Arizona Co-Mentors Harper Price, MDJudith O'Haver, PhD, RN, CPNP-PC, FAANP, FAAN Phoenix Children's Hospital Overview This study hopes to assess how early life experiences can affect a skin condition called atopic dermatitis (AD). Information on both … [Read more...] about The Influence of Childhood Experiences on Exacerbations of Atopic Dermatitis
T regulatory cell dysfunction and Staphylococcus aureus infection enable atopic dermatitis onset and progression
Principal Investigator: Hazel Wilkie, PhD Boston Children's Hospital Overview: Atopic dermatitis (AD, also called allergic eczema) affects 20% of children and 10% of adults. The dry, red, itchy skin lesions are often infected with bacteria. Intriguingly, skin bacterial burden increases prior … [Read more...] about T regulatory cell dysfunction and Staphylococcus aureus infection enable atopic dermatitis onset and progression
Childhood Atopic Dermatitis: The Role of Outdoor Air Pollution on Disease Burden and Racial and Ethnic Disparities
Principal Investigator: Emily Croce, PhD, MSN, ADPRN, NPNP-CP The University of Texas at Austin Overview: Atopic dermatitis (AD) is the most common chronic childhood skin disease and there are significant and persistent racial and ethnic disparities in atopic dermatitis (AD) among children … [Read more...] about Childhood Atopic Dermatitis: The Role of Outdoor Air Pollution on Disease Burden and Racial and Ethnic Disparities
Post-Market Surveillance of the Safety of Systemic JAK Inhibitors for Dermatologic Diseases in Children
Principal Investigator: Jeff Yu, MD Massachusetts General Hospital Overview: Oral Janus Kinase inhibitors (JAKi) are novel therapeutic options for patients with various inflammatory skin conditions, such as alopecia areata, atopic dermatitis, and psoriasis. Currently, most of the data that … [Read more...] about Post-Market Surveillance of the Safety of Systemic JAK Inhibitors for Dermatologic Diseases in Children
Evaluation of the Efficacy of Popular Over the Counter Ointments in Atopic Dermatitis: A Double Blinded Randomized Controlled Trial
Principal Investigator: JiaDe Yu, MDMassachusetts General Hospital Overview: Atopic dermatitis (AD) or eczema is a common skin disease seen in 20% or more of children in the United States. There are many potential causes of AD but disorders in the skin barrier leads to increased water loss … [Read more...] about Evaluation of the Efficacy of Popular Over the Counter Ointments in Atopic Dermatitis: A Double Blinded Randomized Controlled Trial
Neonatal Cutaneous Microbiome Predictors of Infantile Eczema
Principal Investigator: Jennifer Schoch, MD University of Florida Overview: Though the cause of eczema is yet unknown, animal studies suggest importance of the early interaction between bacteria present on the skin and the immune system. If bacteria are present on the skin of mice shortly … [Read more...] about Neonatal Cutaneous Microbiome Predictors of Infantile Eczema