N-Acetylcysteine for Habit – Based Cutaneous Conditions: A Review of Real-World Use in the Pediatric Population

Overview

The aim of this study is to (1) establish the breadth of habit-driven skin disorder diagnosis treated at CHOP with oral Nacetylcysteine, (2) determine dosing range and length of benefit in these patient populations, and (3) determine any potential side effects of oral N-acetylcysteine in real-world use. By doing this, we will be able to provide better recommendations on the use of oral N-acetylcysteine to treat many dermatologic disorders in pediatric populations – an area of treatment that has not yet been fully explored. The Children’s Hospital of Philadelphia (CHOP) database will be the source of patient data (100s of eligible patients expected), and the project will have personnel support from CHOP pediatric dermatologists and the Penn Department of Dermatology.

Status

This project was funded through a 2022 PeDRA Research Fellowship Grant.